Bromocriptine as sole treatment for acromegaly.
نویسندگان
چکیده
منابع مشابه
Bromocriptine-induced psychosis in acromegaly.
Dopaminergic mechanisms have been implicated in the pathogenesis of schizophrenia.' Psychosis induced by the dopamine-receptor agonist bromocriptine has been described mainly with high-dose regimens in Parkinsonism and less frequently with the lower doses used in hormonal disorders.24 The following case is of interest because of the insidious onset of psychosis and the family history of paranoi...
متن کاملPrediction of response to bromocriptine in acromegaly.
BROMOCRIPTINE was first used in the treatment of acromegaly in 1974 (Liuzzi et al, 1974 a). Not all patients show lowered human growth hormone in response to the drug (Liuzzi et al, 1974 a; Thorner and Besser, 1975; Sachdev et al, 1975). We have performed a series of tests on acromegalic patients in an attempt to discover if any test could predict those patients likely to show !ong-term respons...
متن کاملThe Combination Therapy with Bromocriptine and Cyproheptadine in Patients with Acromegaly
The therapeutic efficacy of the combination of cyproheptadine and bromocriptine was studied in 15 patients with active acromegaly showing incomplete GH suppression in response to bromocriptine therapy alone. The mean basal plasma GH was 31.3±5.5 µg/L, and it decreased to 19.0±3.9 µg/L during the single bromocriptine therapy (10-20 mg for 2 to 21 months). When cyproheptadine (12 to 16 mg for 8 t...
متن کاملCurrent treatment guidelines for acromegaly.
Acromegaly, an indolent disorder of growth hormone (GH) hypersecretion is most typically caused by a somatotroph cell adenoma and may be treated by several modalities. Transsphenoidal surgical resection of micro-adenomas by experienced neurosurgeons results in biochemical normalization (postglucose GH <2 ng/mL, assay-dependent, age- and sex-matched IGF-I levels) in 70% of patients. However, ove...
متن کاملBromocriptine for the treatment of peripartum cardiomyopathy.
Peripartum cardiomyopathy (PPCM) is a pregnancyassociated idiopathic cardiomyopathy presenting during pregnancy or within few months after delivery1,2 with signs and symptoms of heart failure caused by marked depression of left ventricular (LV) systolic function. Although the disease is uncommon, it is increasing in frequency3 and represents an important cause of pregnancy-related morbidity and...
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ژورنال
عنوان ژورنال: BMJ
سال: 1980
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.280.6209.254